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CIK - Cytokine-induced killer
Universität Bonn
Universitätsklinikum Bonn

Clinical trials using CIK cells with tumor entity and number of patients

Tumor entity

Reference

Phase

Total number of patients treated with CIK cells

Hepatocellular carcinoma M. Shi et al., 2004 na 13
Olioso et al., 2009 pilot 1
Hui, Qiang, Jian, Ti, & Da-Lu, 2009 na 84
C. Pan et al., 2010 na 42
Hao et al., 2010 na 72
J. Yu et al., 2011 na 2
Niu et al., 2011 na 1
P. Zhou et al., 2011 I 10
Qiu et al., 2011 na 9
Jinying Zhang et al., 2012 retrospective 2
K. Pan et al., 2013 retrospective 204
X. Yu et al., 2014 II 66
Z. Zhang et al., 2015 retrospective 2
Lee et al., 2015 III 114
Y. Liu et al., 2016 retrospective 3
Jian Zhang et al., 2018 retrospective 20
C.-L. Chen et al., 2018 I 9
Z. Zhou, Qin, Weng, & Ni, 2019 retrospective 35
Yoon et al., 2019 IV 59
C. Li et al., 2019 na 11

Renal cell carcinoma

Schmidt-Wolf et al., 1999 I 1
Olioso et al., 2009 pilot 5
Su et al., 2010 na 16
Jinying Zhang et al., 2012 na 10
Zhan et al., 2012 na 46
L. Liu et al., 2012 na 74
Y. Zhang et al., 2013 na 10
Z. Wang et al., 2014 na 29
D. Wang et al., 2014 na 28
X. Zhao et al., 2015 na 61
Zheng et al., 2015 na 154
Hong, Na-na, & Xin-hua, 2016 na 20
C.-L. Chen et al., 2018 I 8
Mai et al., 2018 retrospective 19
Z. Wang et al., 2018 na 1
C. Li et al., 2019 na 6
Acute lymphoblastic leukemia Introna et al., 2007 I 1
Laport et al., 2011 na 2
Y. Linn et al., 2012 I / II 3
Y. Luo et al., 2016 I 2
Introna et al., 2017 II a na
Acute myelogenous leukemia Introna et al., 2007 I 4
Introna et al., 2010 na 4
Laport et al., 2011 na 3
B. Yang et al., 2012 pilot 1
Y. Linn et al., 2012 I / II 8
Dong et al., 2012 na 21
Y.-C. Linn et al., 2012 I / II 13
Y. Wang et al., 2013 na 2
Y. Luo et al., 2016 I 4
Introna et al., 2017 II a na
Narayan et al., 2019 II 12
Chronic lymphoblastic leukemia Laport et al., 2011 na 2
Chronic myelogenous leukemia Introna et al., 2007 I 1
B. Yang et al., 2012 pilot 3
Y. Linn et al., 2012 I / II 1
Y.-C. Linn et al., 2012 I / II 11
Y. Luo et al., 2016 I 3
Lymphoma Schmidt-Wolf et al., 1999 I 2
Leemhuis, Wells, Scheffold, Edinger, & Negrin, 2005 I 9
Introna et al., 2007 I 3
Olioso et al., 2009 pilot 6
Guo et al., 2011 na 8
J. Yu et al., 2011 na 1
Laport et al., 2011 na 6
Y. Linn et al., 2012 I / II 4
Jinying Zhang et al., 2012 na 1
B. Yang et al., 2012 pilot 9
Lu et al., 2012 na 9
Qiu et al., 2016 na 14
Y. Luo et al., 2016 I 4
F. Chen et al., 2017 na 3
Introna et al., 2017 II a na
Pfeffermann et al., 2018 na 1
Bladder cancer Jinying Zhang et al., 2012 na 1
C.-L. Chen et al., 2018 I 2
Breast cancer Niu et al., 2011 na 1
Jinying Zhang et al., 2012 na 1
K. Pan et al., 2014 retrospective 45
Ren et al., 2013 na 87
Hong et al., 2016 na 9
F. Chen et al., 2017 na 8
C.-L. Chen et al., 2018 na 1
C.-L. Chen et al., 2018 na 4
Cervival cancer Niu et al., 2011 na 1
N. Li et al., 2019 na 44
Colorectal cancer Niu et al., 2011 na 2
Jinying Zhang et al., 2012 na 4
Y. Zhu et al., 2013 retrospective 21
H. Zhu et al., 2014 na 100
Gao et al., 2014 na na
Jinying Zhang et al., 2014 na 30
Z. Zhang et al., 2015 retrospective 5
Lin, Song, Chuo, Zhang, & Zhao, 2016 prospective 134
H. Zhao et al., 2016 II 61
Y. Liu et al., 2016 retrospective 18
C. Zhang et al., 2017 na 3
Xie et al., 2017 retrospective 71
C.-L. Chen et al., 2018 I 6
C. Li et al., 2019 na 12
C.-L. Chen et al., 2018 I 6
Esophagus cancer Z. Zhang et al., 2015 retrospective 1
Y. Liu et al., 2016 retrospective 7
C. Zhang et al., 2017 na 1
Gallbladder cancer Niu et al., 2011 na 1
Y. Liu et al., 2016 retrospective 4
Gastric cancer J. Jiang et al., 2006 na 32
J.-T. Jiang et al., 2010 na 75
J. Yu et al., 2011 na 2
Jinying Zhang et al., 2012 na 6
L. Shi et al., 2012 na 74
H. Liu, Song, Yang, & Zhang, 2013 na 51
H. Zhao et al., 2013 retrospective 53
Gao et al., 2014 na na
Z. Zhang et al., 2015 retrospective 1
Cui et al., 2015 pilot 30
Y. Liu et al., 2016 retrospective 14
Xu et al., 2016 II 16
Mu et al., 2016 na 13
Hong et al., 2016 na 6
Y. Chen et al., 2016 retrospective 95
C. Li et al., 2019 na 19
Qiao et al., 2019 prospective 30
Glioblastoma Kong et al., 2017 III 91
F. Chen et al., 2017 na 1
Lung cancer Wu, Jiang, Shi, & Xu, 2008 prospective 29
Hui Li et al., 2009 na 42
J. Yu et al., 2011 na 9
Zhong, Teng, Han, & Zhong, 2011 na 14
Niu et al., 2011 na 8
S. B. Shi, Ma, Li, & Tang, 2012 na 30
Jinying Zhang et al., 2012 na 3
R. Li et al., 2012 II 87
L. Yang et al., 2013 na 61
Jin et al., 2014 na 411
Zhong, Han, & Zhong, 2014 prospective 60
J. Zhang et al., 2015 retrospective 60
Z. Zhang et al., 2015 retrospective 1
P. Zhao et al., 2015 na 25
H. Luo et al., 2016 retrospective 70
Hong et al., 2016 na 10
Y. Liu et al., 2016 retrospective 6
L. Zhang et al., 2016 na 21
Gu et al., 2017 na 32
C. Zhang et al., 2017 na 4
F. Chen et al., 2017 na 12
C. Zhang et al., 2017 na 4
Huang et al., 2017 retrospective 22
D. Chen et al., 2018 na 68
C.-L. Chen et al., 2018 I 3
Z. Wang et al., 2018 na 1
C. Li et al., 2019 na 34
Y. Zhao et al., 2019 prospective 95
L. Zhang et al., 2019 II 40
Melanoma Niu et al., 2011 na 2
Jinying Zhang et al., 2012 na 6
Hong Li et al., 2017 na 55
F. Chen et al., 2017 na 1
Hong et al., 2016 na 4
Multiple myeloma Laport et al., 2011 na 3
X. Zhou et al., 2013 na 2
Y. Liu et al., 2016 retrospective 1
Y. Luo et al., 2016 I 2
Introna et al., 2017 II a na
Myelodysplastic syndrome B. Yang et al., 2012 pilot 5
Introna et al., 2007 I 2
Introna et al., 2017 II a na
Narayan et al., 2019 II 27
Nasopharyngeal carcinoma Y. Li et al., 2015 retrospective 112
C.-L. Chen et al., 2018 I 1
J.-J. Zhao et al., 2018 retrospective 85
Ovarian cancer Niu et al., 2011 na 1
J. Liu et al., 2014 na 46
Z. Zhang et al., 2015 retrospective 4
C. Zhang et al., 2017 na 2
C.-L. Chen et al., 2018 I 1
Y. Zhou et al., 2019 retrospective 72
Pancreatic cancer Jinying Zhang et al., 2012 na 3
M. Wang, Shi, Qi, Tang, & Tian, 2013 prospective 28
Chung, Park, Bang, Park, & Song, 2014 II 20
Z. Zhang et al., 2015 retrospective 1
Z. Wang et al., 2016 retrospective 25
N. Jiang et al., 2017 prospective 36
C. Li et al., 2019 na 2
Prostate cancer J. Yu et al., 2011 na 1
Sarcoma J. Yu et al., 2011 na 1
Jinying Zhang et al., 2012 na 2
F. Chen et al., 2017 na 2
Hong et al., 2016 na 1
Thyroid cancer J. Yu et al., 2011 na 4
Ureter cancer Jinying Zhang et al., 2012 na 1
Total 4551